After reviewing 10 pharmacies, our pick for buying Methotrexate is Amazon Pharmacy at $17.45. Here's our full analysis.
Last updated: April 14, 2026
Our Verdict
For most people buying Methotrexate, we recommend Amazon Pharmacy at $17.45 for a 30-day supply. Online pharmacies typically offer the best prices, though you'll need to wait for delivery.
#1 Pick
online pharmacy
$17.45
$12.20 w/ card
Pros
Cons
#2 Pick
mail-order pharmacy
$18.21
$13.43 w/ card
Pros
Cons
#3 Pick
retail pharmacy
$19.43
$13.09 w/ card
Pros
Cons
| Discount Card | Per Unit | ||||
|---|---|---|---|---|---|
AP Amazon Pharmacy online | $17.45 | $12.20 | $0.5817 | Save $17.31 | Get Price |
C Capsule mail-order | $18.21 | $13.43 | $0.6070 | Save $16.55 | Get Price |
CP Costco Pharmacy retail | $19.43 | $13.09 | $0.6477 | Save $15.33 | Get Price |
HH Honeybee Health mail-order | $19.69 | $14.87 | $0.6563 | Save $15.07 | Get Price |
WP Walmart Pharmacy retail | $20.69 | $14.76 | $0.6897 | Save $14.07 | Get Price |
ES Express Scripts mail-order | $20.97 | $17.60 | $0.6990 | Save $13.79 | Get Price |
CP Cost Plus Drugs online | $22.45 | $18.77 | $0.7483 | Save $12.31 | Get Price |
RA Rite Aid retail | $31.24 | $23.31 | $1.0413 | Save $3.52 | Get Price |
W Walgreens retail | $33.50 | $23.50 | $1.1167 | Save $1.26 | Get Price |
CP CVS Pharmacy retail | $34.76 | $27.33 | $1.1587 | Get Price |
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This guide is for informational purposes only. Consult your physician or pharmacist for medical decisions. Prices are estimates and may vary.